Author Archive for audreyl

Ye Cannae Change the Laws of Physics: Or Can You?

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From The Economist,

Richard Feynman, Nobel laureate and physicist extraordinaire, called it a “magic number” and its value “one of the greatest damn mysteries of physics”. The number he was referring to, which goes by the symbol alpha and the rather more long-winded name of the fine-structure constant, is magic indeed. If it were a mere 4% bigger or smaller than it is, stars would not be able to sustain the nuclear reactions that synthesise carbon and oxygen. One consequence would be that squishy, carbon-based life would not exist.

Why alpha takes on the precise value it has, so delicately fine-tuned for life, is a deep scientific mystery. A new piece of astrophysical research may, however, have uncovered a crucial piece of the puzzle. In a paper just submitted to Physical Review Letters, a team led by John Webb and Julian King from the University of New South Wales in Australia present evidence that the fine-structure constant may not actually be constant after all. Rather, it seems to vary from place to place within the universe. If their results hold up to the scrutiny, and can be replicated, they will have profound implications—for they suggest that the universe stretches far beyond what telescopes can observe, and that the laws of physics vary within it. Instead of the whole universe being fine-tuned for life, then, humanity finds itself in a corner of space where, Goldilocks-like, the values of the fundamental constants happen to be just right for it.

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Darwin’s Method: Induction, Deduction, or Synthesis?

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From The Box Move,

From Becquerel’s uranium rock to Newton’s proverbial apple and Fleming’s serendipitous observation of penicillin, the way science is done has come to be associated often with a romanticized but highly suspect notion of objectivity. This may very well be the effect on science of inductivism and the bold claim of the proponents of inductivism that science could not possibly lead to any kind of truthful explanation of the world around us without it. The questions any historian of science must then ask are: to what extent does objectivity, as surely as it is the hallmark of science, lead to the best scientific discoveries and further, how do we weight the role of accident, hunch, intuition, experimenters’ bias in the role of science especially if they happen to lead us to the right conclusion?

Charles Darwin in his Autobiography stated that he had ‘worked on true Baconian principles…collected facts on a whole-sale scale…and by extensive reading’. Such a canonical biography may be appealing but it is also a dangerous way of approaching history. At some point it must be recognized that evolution by natural selection was not the result of years of observation in which Darwin had no working hypothesis, but instead years of observations geared towards designing proofs for a hypothesis based on little more than a hunch; a frantic search on ‘the species question’ that ensued as little more than a rat race with Alfred Russell Wallace. This is all counter to the inductive procedure. Stephen Jay Gould concurs – in his essay ‘Darwin’s middle road’, Gould argues that Darwin was no inductivist but instead marshaled evidence from many different aspects:

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The Quantification of Everything

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From Vlatko Verdal, Five Books

The quantum information theory professor says there is nothing distinctly novel that was brought to philosophy by quantum mechanics. The key tenet is this randomness that is at the core of our interaction with the world: there is an element that you can never make more deterministic. And, of course, randomness as a way of looking at the world has existed for a long time. He chooses books on quantifying the universe.

Your first book is Quantum Physics: Illusion or Reality? by Alastair Rae. This is a completely popular book about quantum physics: there is not a single equation in there, I think. What he does is to go through all the major ways in which we try to understand quantum physics, all the major interpretations. It’s extremely good in that he writes in a very objective way and it’s very difficult to tell which one he supports. It’s very passionately argued as well, and it’s a beautiful exposition, very philosophical. I think it’s the best, probably my favourite, popular account of all the things we argue about on the fundamental side of quantum physics.

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The Human Genome at Ten

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From Nature

Nearly a decade on from the completion of the draft sequence of the human genome, researchers should work with the same intensity and focus to apply the results to health.

The race to complete the first human genome sequence had everything a story needs to keep its audience enthralled — right down to a neck-and-neck sprint for the finish by two fierce rivals. In the end, the result was basically a tie. The rivals — the international, publicly funded Human Genome Project and the private, for-profit company Celera Genomics then based in Rockville, Maryland — jointly announced the completion of their draft sequences in June 2000 at a gala televised press conference attended by US President Bill Clinton and UK Prime Minister Tony Blair.

The White House press statement articulated the hope, felt by many, that this landmark achievement would “lead to a new era of molecular medicine, an era that will bring new ways to prevent, diagnose, treat and cure disease”.

This issue of Nature takes a look at the next chapter in the story — the first post-genome decade — then asks how the tale might unfold in the years to come.

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Collaborating with Citizen Scientists

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From Lucas Laursen, Science

Climbing one of the world’s biggest granite walls is different from climbing trees, as National Park Service botanist Martin Hutten discovered while dangling from a cliff in the spray of Vernal Falls high above the Yosemite Valley. Hutten apprenticed in the logging industry before he started graduate school, so he new how to climb trees. “I could trust myself to a rope,” he recalls, “but I’d definitely never hung off a cliff or collected [samples] from a cliff.”

So when Hutten — who is seeking a Ph.D. in forest ecology at Oregon State University, Corvallis — and his fellow park rangers needed help surveying the park’s lichen, they enlisted experienced rock climbers. Over 2 weeks in 2007 and 2008, those volunteer climbers helped collect 394 lichen specimens. This year, the researchers are asking volunteers to help with other parts of their biodiversity survey, such as counting birds from the valley floor.

Hutten’s project is one of many worldwide in which volunteers help scientists collect data in ways that range from mundane to vital. Such help, although voluntary, is not free. Recruiting volunteers, finding appropriate ways for them to contribute, training them, keeping them motivated, and ensuring the quality of the data they collect requires time, money, and management expertise.

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Audacity, Part 5: Rejection and Ridicule

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From Anne Sasso, Science

Almost all important breakthroughs encounter resistance from other scientists, who have a tendency — justifiable for the most part — to defend the status quo. Some insights are resisted with such intensity that it may take decades before they’re widely accepted among scientists. For some, such as HIV, heliocentrism, and evolution, pockets of resistance remain decades or centuries after the war is won.

It follows that if you’re determined to take on audacious scientific projects, you need to be ready for the fallout. Scientists committed to incremental advances may work for decades without attracting any enmity. But as soon as your data show that you might be on to something game-changing, be prepared for a new level — and type — of challenge. Are you ready to have the top scientists in your field criticizing your work in journals and dissing you at meetings? Because history shows that the deeper your idea cuts into the heart of a field, the more your peers are likely to challenge you. Human nature being what it is, what ought to be reasoned discussion may turn personal, even nasty.

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Science Economics: What Science is Really Worth

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From Colin Macilwain, Nature News

Spending on science is one of the best ways to generate jobs and economic growth, say research advocates. But as Colin Macilwain reports, the evidence behind such claims is patchy.

President Barack Obama says it. Francis Collins, director of the US National Institutes of Health (NIH), says it. University and research leaders elsewhere are saying it, too. The number one current rationale for extra research investment is that it will generate badly needed economic growth.

“Science is more essential for our prosperity, our health, our environment and our quality of life than it has ever been before,” said Obama, addressing the National Academy of Sciences in Washington DC last year. Getting down to the details, Collins has recently cited a report by Families USA, a Washington DC-based health-advocacy group, which found that every US$1 spent by the NIH typically generates $2.21 in additional economic output within 12 months.

“Biomedical research has generally been looked at for its health benefits, but the case for it generating economic growth is pretty compelling,” says Collins. In Britain, senior scientists have called on the government to support science as a means of helping the economy out of recession. Heeding such arguments, governments in Germany, Sweden, Canada and Australia, as well as the United States, have increased research spending as part of stimulus packages designed to aid their struggling economies.

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The Explorer: Jacques Cousteau’s Association with Nature Often Masks his Interest in Civilization

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From Stefany Anne Golberg, The Smart Set

The final episode of The Jacques Cousteau Odyssey begins not in the sea but in the sky. Sideways, we soar though the clouds, glimpsing a solitary island below, far into the Pacific. As always, we hold our breath in anticipation. A couple of years before “Clipperton: The Island Time Forgot” first aired, Jacques Cousteau gave his son and trusty costar Philippe a PBY seaplane named Flying Calypso, after Cousteau’s famous boat, Calypso. It was a fatherly gesture to a son who lived in his father’s shadow. The plane was meant to distinguish Philippe, whose true love was flight.

Eventually, we land. A menacing army of poisonous crabs mans the shoreline. The camera pans to a couple of rusted shipwrecks and some abandoned shacks, which are now perches for some booby birds. “Human beings have come and gone, leaving mute evidence of their troubled presence,” the narrator intones. This is what the remote island has to offer: some intimidating crabs, a flock of booby birds, the wreckage of failed attempts at civilization. In the final episode of The Jacques Cousteau Odyssey, the story of man and the story of nature will intertwine; melancholy, futile, but beautiful all the same.

Then, music! That triumphant theme song that trumpets, WE ARE ALL GOING ON AN ADVENTURE AND IT’S GOING TO RULE! Dah dah dah dah daaah! That music represents everything the whole world loves about Jacques Cousteau. It’s what we will blast on June 10, when we all grab a bottle of champagne and toast Jacques Cousteau on what would have been his 100th birthday.

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Designing Minds: How Should we Explain the Origins of Novel Behaviors?

From Edward A. Wasserman and Mark S. Blumberg, American Scientist

The basic argument of intelligent design was famously set forth in the watchmaker analogy of William Paley in 1802: The complexity and functionality of a watch imply a watchmaker; analogously, the complexity and functionality of living things also imply a designer, albeit one vastly more potent than a mere watchmaker. This argument rests on a simple analogy between the design of human artifacts and the design of natural forms. For the analogy to work, we must first accept that we design our inventions with purpose and foresight. On this point, most evolutionists and creationists agree. What distinguishes these two camps is that, when accounting for the origin of living things, proponents of intelligent design summon a divine creator, whereas evolutionists credit natural selection. Thus, evolutionists share with creationists the same understanding of design; they differ only in how they invoke it.

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Daring to Discuss Women in Science

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From John Tierny, The New York Times

The House of Representatives has passed what I like to think of as Larry’s Law. The official title of this legislation is “Fulfilling the potential of women in academic science and engineering,” but nothing did more to empower its advocates than the controversy over a speech by Lawrence H. Summers when he was president of Harvard.

This proposed law, if passed by the Senate, would require the White House science adviser to oversee regular “workshops to enhance gender equity.” At the workshops, to be attended by researchers who receive federal money and by the heads of science and engineering departments at universities, participants would be given before-and-after “attitudinal surveys” and would take part in “interactive discussions or other activities that increase the awareness of the existence of gender bias.”

I’m all in favor of women fulfilling their potential in science, but I feel compelled, at the risk of being shipped off to one of these workshops, to ask a couple of questions:

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Marilynne Robinson: Can Science Solve Life’s Mysteries?

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From The Guardian

It will be a great day in the history of science if we sometime discover a damp shadow elsewhere in the universe where a fungus has sprouted. The mere fossil trace of life in its simplest form would be the crowning achievement of generations of brilliant and diligent labour. And here we are, a gaudy efflorescence of consciousness, staggeringly improbable in light of everything we know about the reality that contains us. There are physicists and philosophers who would correct me. They would say, if there are an infinite number of universes, as in theory there could be, then creatures like us would be very likely to emerge at some time in one of them. But to say this is only to state the fact of our improbability in other terms.

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Artificial Brains are Imminent…Not!

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From John Horgan, Scientific American

Scientists are on the verge of building an artificial brain! How do I know? Terry Sejnowski of the Salk Institute said so right here on ScientificAmerican.com. He wrote that the goal of reverse-engineering the brain—which the National Academy of Engineering recently posed as one of its “grand challenges”—is “becoming increasingly plausible.” Scientists are learning more and more about the brain, and computers are becoming more and more powerful. So naturally computers will soon be able to mimic the brain’s workings. So says Sejnowski.

Sejnowski is a very smart guy, whom I’ve interviewed several times over the years about the mysteries of the brain. But I respectfully—hell, disrespectfully, Terry can take it—disagree with his prediction that artificial brains are imminent. Sejnowski’s own article shows how implausible his prediction is. He describes two projects—both software programs running on powerful supercomputers—that represent the state of the art in brain simulation. On the one hand, you have the “cat brain” constructed by IBM researcher Dharmendra Modha; his simulation contains about as many neurons as a cat’s brain does organized into roughly the same architecture. On the other hand, you have the Blue Brain Project of Henry Markram, a neuroscientist at the Ecole Polytechnique Fédérale de Lausanne.

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Dr. Craig Venter Shakes the Heavens with Synthetic Life

Image from Popular Science

Image from Popular Science

From Jordan Manalatas, Daily Bruin

If imitation is the highest form of flattery, what then are we to make of Dr. Craig Venter’s recent stab at God? La Jolla’s own mad scientist and crew might just give the Big Guy a run for his money, raising all sorts of moral crises, ethical dilemmas and plumbings of faith.

Team Venter shook the scientific world last week with its announcement of the first successfully synthesized self-replicating bacterium. The bacterium in question – a chimeric copy of Mycoplasma mycoides, genomically synthesized and injected into a recipient cell – has a new nickname (Synthia) and an even louder reputation (the first synthetic life form).

Like Mary Shelley’s pithy Prometheus, our Dr. Venterstein has done what was once the sole domain of the gods – that is, creating new life. A product of synthetic genomic engineering, Synthia is perhaps the first creature since Jesus to lack proper earthly parents.

The DNA she bears was not written by God or nature, but by our Craig and his cronies at the J. Craig Venter Institute, on a computer. Somewhere in her genome lie some James Joyce quotes and an e-mail address, coded in the language of life itself.

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James Joyce’s Words Come To Life, And Are Promptly Desecrated

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From Discover,

This old English major’s heart is warmed by the news that the new synthetic cell carries a line from James Joyce, inscribed in its DNA: “To live, to err, to fall, to triumph, to recreate life out of life.”

What would Joyce have thought if someone had told him that one day the synthesized genome of a goat pathogen would carry his words? I would hope that whoever told him would make sure that he did not think this moment marked his literary immortality. In fact, his deathless prose is probably being desecrated by the relentless erosion of evolution right now.

The scientists who produced the new synthetic cell copied the genome of a microbe, letter for letter, and then inserted the synthetic version into a host cell. To determine that their experiment worked, they needed a way to tell the genomes of their synthetic cells from the natural genomes that were their model. So they inserted “watermarks” into the artificial genome. These sequences of DNA (which spelled out the work of Joyce and others through the genetic code) sit in non-coding regions of the microbe’s DNA. As a result, these watermarks cannot disrupt any essential protein-coding genes or stretches of DNA that are vital for switching genes on and off.

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‘Artificial Life’ Breakthrough Announced by Scientists

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From Victoria Gill, BBC News

Scientists in the US have succeeded in developing the first living cell to be controlled entirely by synthetic DNA.

The researchers constructed a bacterium’s “genetic software” and transplanted it into a host cell.

The resulting microbe then looked and behaved like the species “dictated” by the synthetic DNA.

The advance, published in Science, has been hailed as a scientific landmark, but critics say there are dangers posed by synthetic organisms.

Some also suggest that the potential benefits of the technology have been over-stated.

But the researchers hope eventually to design bacterial cells that will produce medicines and fuels and even absorb greenhouse gases.

The team was led by Dr Craig Venter of the J Craig Venter Institute (JCVI) in Maryland and California.

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Peering Inside the Social Brain

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From Siri Carpenter, Science

What makes it possible for people to love, hate, help, or betray one another? How do we decode facial expressions? How do we understand and regulate our own emotional experiences? How do we separate the self from the other, make moral judgments, or decide how much money to save for retirement? What causes some people to turn to religious extremism, heroin, or politics? How does the brain fail those with social deficits such as autism?

Questions like these sit at the junction of our social, emotional, and biological realities, and they drive the young but rapidly growing field of social neuroscience.

Until a few years ago, the idea that science could elucidate the neural foundations of social phenomena as complex as love, friendship, and trust “just basically seemed ludicrous,” says Janine Simmons, chief of the National Institute of Mental Health’s (NIMH’s) program for affect, social behavior, and social cognition. Such “big questions” motivate many scientists to study neuroscience or psychology, she says — but soon they realize that the ability to address such questions is limited by technology. “It’s just recently that people have not been laughed at for taking on these more complex questions,” she says.

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Doomsayers Beware, a Bright Future Beckons

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From John Tierney, The New York Times

Long before “sustainable” became a buzzword, intellectuals wondered how long industrial society could survive. In “The Idea of Decline in Western History,” after surveying predictions from the mid-19th century until today, the historian Arthur Herman identifies two consistently dominant schools of thought.

The first school despairs because it foresees inevitable ruin. The second school is hopeful — but only because these intellectuals foresee ruin, too, and can hardly wait for the decadent modern world to be replaced by one more to their liking. Every now and then, someone comes along to note that society has failed to collapse and might go on prospering, but the notion is promptly dismissed in academia as happy talk from a simpleton. Predicting that the world will not end is also pretty good insurance against a prolonged stay on the best-seller list. Have you read Julian Simon’s “The State of Humanity”? Indur Goklany’s “The Improving State of the World”? Gregg Easterbrook’s “Sonic Boom”?

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Who Cares What the Experts Say? - The Democratization of Science

From Terry Newell, The Huffington Post

The difficulty during last year’s Copenhagen Climate Summit in reaching agreement on how to address global warming reflects the contentious political environment on even scientific issues. While worrisome to many, there is an even more troubling lack of agreement right here in America on the core scientific question: is global warming real? While 72% of Americans still think global warming is taking place (Washington Post-ABC News Poll, November 2009), that’s down from 80% a year earlier. Among Republicans, only 54% believe global warming is happening, down from 76% in 2008. Last year’s revelation that some British scientists “massaged” their data for a published paper on the topic has been used by some (who have labeled it “Climategate”) to cast doubt on the entire record of scientific research on global climate change.

Can we no longer trust science and scientists? In a December ABC News -Washington Post poll, 40% of respondents said that they could “trust the things that scientists say about the environment” only “a little or not at all.” Sixty-two percent said that there is “a lot of disagreement” among scientists “about whether or not global warming is happening,” a figure far in excess of the disagreement that actually exists.

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Adventures of a Man of Science: Moretti in California

From Elif Batuman, n+1imagephp

Franco Moretti, Graphs, Maps, Trees: Abstract Models for a Literary History. Verso, 2005.

A specter is haunting the academy—the specter of close reading. But don’t worry: as the New York Public Library had the Ghostbusters, the academy has Franco Moretti.

Of course, Moretti is not the first or the only critic to object to close reading. For a good fifteen years, close reading has had a place in the ever-expanding group of things that might be bad for you; experts have shown that close reading will cause you to ignore history, reinforce cultural hegemonies, and “avoid commitment.”

But Moretti’s objections are different. Moretti is a man of the world, and men of the world do not reproach you for trying to avoid commitment. Instead, he finds close reading to be close-minded, superstitious, a fundamentally “theological exercise—very solemn treatment of very few texts taken very seriously.” The problem with the canon, by extension, is not that it is sexist, racist, or classist, but that it is so-provincial.

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Neurocapitalism

From Ewa Hess and Hennric Jokeit, Eurozine

Today, the neurosciences enjoy a similar prestige as psychoanalysis in the twentieth century, write Hennric Jokeit and Ewa Hess. Despite the immense costs for healthcare systems, the fear of depression, dementia and attention deficit disorder legitimises the boom in neuro-psychotropic drugs. In a performance-driven society that confronts the self with its own shortcomings, neuroscience serves an expanding market.

Today, the phenomenology of the mind is stepping indignantly aside for a host of hyphenated disciplines such as neuro-anthropology, neuro-pedagogy, neuro-theology, neuro-aesthetics and neuro-economics. Their self-assurance reveals the neurosciences’ usurpatory tendency to become not only the humanities of science, but the leading science of the twenty-first century. The legitimacy, impetus and promise of this claim derive from the maxim that all human behaviour is determined by the laws governing neuronal activity and the way it is organised in the brain.

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The Obama Administration Unveils its Controversial New Plan for the Future of NASA’s Human Spaceflight Program

From Lee Billings, Seed

By virtue of the fact that our ancient evolutionary ancestors were graced with five digits on two forelimbs, we humans now have two five-fingered hands, and most of us count in base-10 notation. Consequently, certain temporal milestones are more appealing than others. For instance, media stories this week commemorated the 40th anniversary of Apollo 13, the legendary lunar mission where three astronauts trapped in a malfunctioning spacecraft were saved through an inspiring combination of luck, ingenuity, and teamwork.wir_4_16_10_sqr

This week also saw the 29th anniversary of the first space shuttle launch, as well as the 49th anniversary of Vostok 1, the flight that took the first human into outer space. But, thanks to our ten-fingered ways we’ll all wait until next year to celebrate. So it goes in any product of biological evolution—seemingly insignificant initial events cast shadows measured in eons. This holds true for technological progress, too: Early decisions in development or deployment become locked in, constraining later features and capabilities. Consider NASA: Today’s extremely expensive and somewhat unsatisfying staples of US human spaceflight, the space shuttle and a space station, can be traced back forty years or so to the aftermath of the Apollo program, when President Nixon chose them as its replacements. The legacy of these choices is that no one has ventured beyond low-Earth orbit ever since.

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US: Women Gain in Science While Video Games Hold Back Boys

From John Richard Schrock, University World News

The number of women taking courses in science, technology, engineering and mathematics, the STEM subjects, has been increasing since 1966 according to a new report. But another study, on boys’ academic responses to new video games, establishes a cause-and-effect relationship that could partly explain the decline in male academic achievement.boy-playing-video-games-fun1

Women students in higher education now outnumber men in most countries, except Japan and Turkey. In the US, this has skewed the ratio among the sexes in terms of those who graduate: the proportion of males earning degrees has dropped to 43% while that for women has increased to 57%.

Women students have long dominated the humanities, with men still the majority in STEM. But while women have traditionally prevailed in professions such as nursing and teaching, veterinary and medical schools are now experiencing a flood of women students.

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Redesigned Newsletter: Launched Today

Today the Science Newsletter will be re-launched – marking the start of a new approach to connecting with and reaching out to our Science Community. The newsletter will be sent out on a monthly basis and will contain important community news, conference updates, and publication information.

It is the hope of Common Ground Publishing that this newsletter will provide you with a more positive experience connecting with the Science Community.

If you are not currently a subscriber but would like to receive future newsletter emails, please go to science-society.com and click on “Sign Up: Our Newsletter” in the upper right-hand corner.

If you have inquiries, concerns, or general comments, please feel free to contact the newsletter team at support@science-society.com.

The Moral Equivalent of the Parallel Postulate

From Sean, Discover

Sam Harris gave a TED talk, in which he claims that science can tell us what to value, or how to be moral. Unfortunately I completely disagree with his major point. (Via Jerry Coyne and 3 Quarks Daily.)

He starts by admitting that most people are skeptical that science can lead us to certain values; science can tell us what is, but not what ought to be. There is a old saying, going back to David Hume, that you can’t derive ought from is. And Hume was right! You can’t derive ought from is. Yet people insist on trying.

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The Second International Conference on Science in Society

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The 2010 Science in Society will be held at the Carlos III University of Madrid, Madrid, Spain from 11-13 November.

Plenary Speakers

  • Dr. Matthew Stanley, New York University, New York, USA
  • Dr. Fernando Broncano, Carlos III University, Madrid, Spain
  • Dr. Javier Echeverria, Instituto de Filosofía of the Consejo Superior de Investigaciones Científicas, Madrid, Spain
  • Jesus Zamora-Bonilla, UNED, Madrid, Spain
  • Javier Moscoso, CSIC, Madrid, Spain
  • Jimena Canales, Harvard University, Boston, USA
  • Javier Ordonez, Universidad Autonoma de Madrid, Madrid, Spain

Call for Papers

If you intend to present a paper at the conference, your participation begins with submission of a paper proposal. For information on proposals, presentation types, and other options, see: http://science-society.com/conference-2010/call-for-papers/. To submit a proposal, see: http://science-society.com/conference-2010/call-for-papers/. Please note that if your proposal is accepted, you will then need to register for the conference.

Registration

Those who submit paper proposals should register following the acceptance of the proposal. Conference delegates who do not intend to present may register at any time. For registration options or to register for the 2010 Science in Society Conference, see: http://science-society.com/conference-2010/register/.

Themes

Accommodation

http://science-society.com/conference-2010/accommodation/

Activities and Extras

http://science-society.com/conference-2010/activities-and-extras/

2010 Science in Society Conference Accommodation in Madrid - Now Available

Accommodations are now available for the 2010 Science in Society Conference.  Please see the Conference Accommodation webpage for more information. hotel_tryp_leganes_search

Raising Neanderthals: Metaphysics at the Limits of Science

From Daniel Rourke, 3 Quarks Daily

A face to face encounter, devoid of the warm appeal of flesh. The eyes are glass, a cold blue crystal reflects the light in a way real eyes never would. A muzzle of hair, perhaps taken from a barbershop floor or the hind quarters of an animal. The painted scalp 6a00d8341c562c53ef01310fc653f8970c-300wi2peeks through the sparse strands: there is nothing here one might caress with fumbling fingers, or, a millennia ago, pick between to lovingly tease out a louse or mite. The figure balances uneasily on stumps for legs. Its waxen surface bears no resemblance to skin. It is a shade saturated of living colour. In another shortened limb the figure holds a wooden spear, with a plastic point designed to take the place of the authentic stone tip. Under its beaten brow this creature forever stands. He is a spectacle, a museum attraction. He is not human, he is ‘other’. He is not man, he is Neanderthal.

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The Language of Life: DNA and the Revolution in Personalised Medicine

From Peter Forbes, The Guardian

Francis Collins was appointed director of the National Institutes of Health (equivalent of the Medical Research Council) by President Obama in August 2009. He is the Pete Seeger of molecular biology. When he has made a great discovery he writes a song about it. And the connection is not just a matter of uplifting songs: Collins is a geneticist, but his spiritual, emotional and political inheritance comes from Roosevelt’s New Deal (his parents worked with Eleanor Roosevelt), folk music and God, just as much as from Darwin, Mendel and Crick.dna-under-a-microscope-0011

The cover of The Language of Life carries Obama’s endorsement: “His groundbreaking work has changed the very ways we consider our health and examine disease.” His is a brilliant appointment, albeit controversial among some scientists: Collins is the highest-profile scientist and public administrator who is also a proselytising Christian. His previous book, The Language of God, contains both the most concise exposition I have read on why evolution is demonstrable fact and a moving account of his religious conversion from early atheism to strong belief. This stance has brought him into conflict both with Richard Dawkins and with Christian groups in the US. But, as right-wing attacks on evolution and global warming science broaden into a generalised anti-science movement, Collins is an important figure – someone who can wrong-foot people who have polarised attitudes.

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Odds Are, It’s Wrong

From Tom Siegfried, Science News

For better or for worse, science has long been married to mathematics. Generally it has been for the better. Especially since the days of Galileo and Newton, math has nurtured science. Rigorous mathematical methods have secured science’s fidelity to fact and conferred a timeless reliability to its findings.feat_statistics_pvalue_chart

During the past century, though, a mutant form of math has deflected science’s heart from the modes of calculation that had long served so faithfully. Science was seduced by statistics, the math rooted in the same principles that guarantee profits for Las Vegas casinos. Supposedly, the proper use of statistics makes relying on scientific results a safe bet. But in practice, widespread misuse of statistical methods makes science more like a crapshoot.

It’s science’s dirtiest secret: The “scientific method” of testing hypotheses by statistical analysis stands on a flimsy foundation. Statistical tests are supposed to guide scientists in judging whether an experimental result reflects some real effect or is merely a random fluke, but the standard methods mix mutually inconsistent philosophies and offer no meaningful basis for making such decisions. Even when performed correctly, statistical tests are widely misunderstood and frequently misinterpreted. As a result, countless conclusions in the scientific literature are erroneous, and tests of medical dangers or treatments are often contradictory and confusing.

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Ask a Nuclear Physicist: What’s the Difference Between 1,500 and 2,200 Nuclear Weapons?

From Juli Weiner, Vanity Fairnuclear1

Today, Barack Obama and Russian President Dmitry Medvedev agreed to reduce the nuclear arsenals of the United States and Russia, respectively. According to the Huffington Post, “the agreement would require both sides to reduce their arsenals of long-range nuclear weapons by about a third, from 2,200 now to 1,550 each.” The deal was a bona-fide diplomatic victory: “The presidents agreed that the new treaty marks a higher level of cooperation between Russia and the United States in the development of new strategic relations,” said a statement issued by the Kremlin, as reported in The New York Times.

But are 1,500 nuclear weapons any less capable of completely destroying the world than 2,200 nuclear weapons are? VF Daily checked with two Columbia University nuclear physicists to see what difference, if any, 700 nuclear weapons makes.

Gustaaf Brooijmans, experimental high-energy particle physicist, thinks 1,500 nuclear weapons are more than enough to devastate the planet, although annihilation isn’t a sure bet:

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Fundamental Forces and Chopping Wood

From Hartosh Singh Bal, Open Lounge

From Newton to Einstein, understanding gravity has been the holy grail of physics. Professor T Padmanabhan of the Inter University Centre for Astronomy and Astrophysics, Pune, spoke to Open of the work for which he was awarded the 2009 Infosys Prize for the Physical Sciences.
Q Gravity is the force we are most familiar with, yet it remains the most mysterious. What makes it so?4817wood

A We are familiar with two force fields in day-to-day life: electromagnetism and gravity. The first deals with charged bodies and unlike gravity it can be both attractive and repulsive; so it doesn’t increase just because you add more and more material, because matter on the whole is electrically neutral. Gravity, on the other hand, is always attractive, which means that its effect is accumulative. As a result, gravitational systems have a tendency to collapse as they get more and more massive, and there is an inherent instability to gravitational systems. Moreover, if you consider the implications of Einstein’s formula E=Mc2, energy and mass are interrelated, so even energy exerts gravity, and in turn the gravitational field of matter also exerts gravity. As a result, gravity is the only non-linear classical force and is very difficult to work with.

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Should We Clone Neanderthals?

From Zach Zorich, Archaeology,

If Neanderthals ever walk the earth again, the primordial ooze from which they will rise is an emulsion of oil, water, and DNA capture beads engineered in the laboratory of 454 Life Sciences in Branford, Connecticut. Over the past 4 years those beads have been gathering tiny fragments of DNA from samples of dissolved organic materials, including pieces of Neanderthal bone. Genetic sequences have given paleoanthropologists a new line of evidence for testing ideas about the biology of our closest extinct relative. neanderthals15

The first studies of Neanderthal DNA focused on the genetic sequences of mitochondria, the microscopic organelles that convert food to energy within cells. In 2005, however, 454 began a collaborative project with the Max Planck Institute in Leipzig, Germany, to sequence the full genetic code of a Neanderthal woman who died in Croatia’s Vindija cave 30,000 years ago. As the Neanderthal genome is painstakingly sequenced, the archaeologists and biologists who study it will be faced with an opportunity that seemed like science fiction just 10 years ago. They will be able to look at the genetic blueprint of humankind’s nearest relative and understand its biology as intimately as our own.

In addition to giving scientists the ability to answer questions about Neanderthals’ relationship to our own species–did we interbreed, are we separate species, who was smarter–the Neanderthal genome may be useful in researching medical treatments. Newly developed techniques could make cloning Neanderthal cells or body parts a reality within a few years. The ability to use the genes of extinct hominins is going to force the field of paleoanthropology into some unfamiliar ethical territory. There are still technical obstacles, but soon it could be possible to use that long-extinct genome to safely create a healthy, living Neanderthal clone. Should it be done?

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In Mathematician Steven Strogatz’s Recent Book, Friendship and Integrals Collide, Yielding a Math Story of Unusual Poignancy

From Veronique Greenwood, Seed Magazine

Long after Steven Strogatz had become a professor at MIT and Cornell, he was still writing letters to his high school calculus teacher, Don Joffray. The two started swapping word problems and logic puzzles when Strogatz, who studies chaotic systems, was in college. Their jovial mini-treatises form the body of Strogatz’s most recent book, The Calculus of Friendship.

But they always managed to keep a certain distance from each other, demonstrating, perhaps, the natural reserve for which mathematicians are known. Mr. Joffray, as Strogatz still refers to him, sent his congratulations on Strogatz’s engagement in a brief preface to a calculus problem, but Strogatz’s reply makes no acknowledgement. When he heard from secondhand sources that Joffray’s son had died, Strogatz wondered why Joffray never mentioned it, but never brought it up. After thirty years of omissions, it took a string of tragic events to bring their friendship into three dimensions.

Seed editor Veronique Greenwood spoke with Strogatz about the nature of friendship, why math isn’t about right and wrong, and how an elliptical swimming pool helped launch his teaching career.

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Answering “Scientific” Arguments of Animal Rights Extremists

From Science Blogs

I spent a lot of time writing about animal rights extremists who have threatened to harass the children of an investigator whom they view as a “vivisector” and how they fetishize the very violence they decry. Unfortunately, I was disappointed to see that a fellow ScienceBlogger, namely Eric Michael Johnson of The Primate Diaries, appears to share some of the scientific misconceptions that the animal rights extremists when he prefaces an Open Letter to the Animal Liberation Front with:animal_test_rabbits1

Vivisection, or what in polite society is merely called animal experimentation, is a barbaric practice that has led to some necessary medical breakthroughs but has mostly served to profit multinational pharmaceutical and cosmetic corporations. I agree with the researchers who published in the British Medical Journal in 2004 that:

Clinicians and the public often consider it axiomatic that animal research has contributed to the treatment of human disease, yet little evidence is available to support this view.

I am also sympathetic to your frustration that, despite mounting evidence that little is gained from this research, its use continues and even grows.

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Warning: Your Reality is Out of Date

From Samuel Arbesman, Boston.com

When people think of knowledge, they generally think of two sorts of facts: facts that don’t change, like the height of Mount Everest or the capital of the United States, and facts that fluctuate constantly, like the temperature or the stock market close.solar__1267210539_23511

But in between there is a third kind: facts that change slowly. These are facts which we tend to view as fixed, but which shift over the course of a lifetime. For example: What is Earth’s population? I remember learning 6 billion, and some of you might even have learned 5 billion. Well, it turns out it’s about 6.8 billion.

Or, imagine you are considering relocating to another city. Not recognizing the slow change in the economic fortunes of various metropolitan areas, you immediately dismiss certain cities. For example, Pittsburgh, a city in the core of the historic Rust Belt of the United States, was for a long time considered to be something of a city to avoid. But recently, its economic fortunes have changed, swapping steel mills for technology, with its job growth ranked sixth in the entire United States.

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Warning: Your Reality is Out of Date: Introducing the Mesofact

From Samuel Arbesman at Boston.com

When people think of knowledge, they generally think of two sorts of facts: facts that don’t change, like the height of Mount Everest or the capital of the United States, and facts that fluctuate constantly, like the temperature or the stock market close.solar__1267210539_2351

But in between there is a third kind: facts that change slowly. These are facts which we tend to view as fixed, but which shift over the course of a lifetime. For example: What is Earth’s population? I remember learning 6 billion, and some of you might even have learned 5 billion. Well, it turns out it’s about 6.8 billion.

Or, imagine you are considering relocating to another city. Not recognizing the slow change in the economic fortunes of various metropolitan areas, you immediately dismiss certain cities. For example, Pittsburgh, a city in the core of the historic Rust Belt of the United States, was for a long time considered to be something of a city to avoid. But recently, its economic fortunes have changed, swapping steel mills for technology, with its job growth ranked sixth in the entire United States.

These slow-changing facts are what I term “mesofacts.” Mesofacts are the facts that change neither too quickly nor too slowly, that lie in this difficult-to-comprehend middle, or meso-, scale. Often, we learn these in school when young and hold onto them, even after they change. For example, if, as a baby boomer, you learned high school chemistry in 1970, and then, as we all are apt to do, did not take care to brush up on your chemistry periodically, you would not realize that there are 12 new elements in the Periodic Table. Over a tenth of the elements have been discovered since you graduated high school! While this might not affect your daily life, it is astonishing and a bit humbling.

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New York University Professor, Matthew Stanley, speaking in Madrid

www.ScienceinSocietyConference.com

Matthew Stanley teaches and researches the history and philosophy of science. He holds degrees in astronomy, religion, physics, and the historygallatinstanley2 of science, and is interested in the connections between science and the wider culture. He is the author of Practical Mystic: Religion, Science, and A.S. Eddington, which examines how scientists reconcile their religious beliefs and professional lives. Currently, he is writing a book that explores how science changed from its historical theistic foundations to its modern naturalistic ones. Professor Stanley is also developing a project on science in war, and he is part of a nationwide effort to use the humanities to improve science education in the college classroom. He has held fellowships at the Institute for Advanced Study, the British Academy, and the Max Planck Institute.

Can Obama Stop the War on Science?

From Paul Walman, The American Prospect

As a presidential candidate, Barack Obama warmed the hearts of progressives when he promised to change “the posture of our federal government from being one of the most anti-science administrations in American history to one that embraces science and technology.” And when he got into office, he took a number of steps that demonstrated his sincerity. 100112_waldman_lead

He abolished George W. Bush’s restrictions on embryonic stem-cell research and announced that he was “directing the head of the White House Office of Science and Technology Policy to develop a strategy for restoring scientific integrity to government decision making.” His Department of Energy — run by Nobel-winning physicist Steven Chu — is spending hundreds of millions of dollars on exploring innovative new energy sources under its Advanced Research Projects Agency-Energy (ARPA-E), modeled on the Defense Department’s DARPA. Obama also increased spending for the National Science Foundation. And he just announced a $250 million public-private partnership to improve math and science teaching.

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Firing Bullets of Data at Cozy Anti-Science

From Janet Maslin, The New York Times.

“I always say that electricity is a fantastic invention,” the British economist Michael Lipton once told Michael Specter, whose bristling new book, “Denialism,” explores the dangerous ways in which scientific progress can be misunderstood. “But if the first two products had been the electric chair and the cattle prod,” Mr. Lipton continued, “I doubt that most consumers would have seen the point.”articleinline1

Here is what they would have done instead, if Mr. Specter, a staff writer for The New Yorker and former foreign correspondent for The New York Times, correctly captures the motifs that shape the stubbornly anti-scientific thinking for which his book is named: they would have denounced electricity as a force for evil, blamed its prevalence on venal utility companies, universalized the relatively rare horrific experiences of people who have been injured by electrical currents and called for a ban on electricity use.

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Defending Science Isn’t Always Pretty

From Sean, Discover.

This month’s issue of WIRED features a great story by Amy Wallace: “An Epidemic of Fear: How Panicked Parents Skipping Shots Endangers Us All.” It’s an overview of the anti-vaccination movement in the United States, a topic that should be very familiar to anyone who reads Discover’s baddest astronomer. At ScienceBlogs, Orac and Abel Pharmboy gives big thumbs-up to the article.

The anti-vaccination movement is a little weird — they claim that vaccines, which are universally credited with wiping out smallpox and polio and other bad things, are responsible for causing autism and diabetes and other also-bad things, all just to make a buck for pharmaceutical companies. The underlying motivation seems to be a combination of the conviction that things must happen for a reason — if a child develops autism, there must be an enemy to blame — and a general distrust of science and technology. Certainly the pro-science point of view is fairly unequivocal; like any medicine, vaccines should be used properly, but they have done great good for the world and there are very real dangers of increased risk for epidemics if enough children stop receiving them. Good for WIRED for taking on the issue and publishing an uncompromisingly pro-science piece on it.

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The Genesis 2.0 Project

From Kurt Andersen, Vanity Fair.

Among the defining attributes of now are ever tinier gadgets, ever shorter attention spans, and the privileging of marketplace values above all. Life is manically parceled into financial quarters, three-minute YouTube videos, 140-character tweets. In my pocket is a phone/computer/camera/video recorder/TV/stereo system half the size of a pack of Marlboros. And what about pursuing knowledge purely for its own sake, without any real thought of, um, monetizing it? Cute.

And so in our hyper-capitalist flibbertigibbet day and age, the new Large Hadron Collider, buried about 330 feet beneath the Swiss-French border, near Geneva, is a bizarre outlier.hadron-collider-1001-01

The L.H.C., which operates under the auspices of the European Organization for Nuclear Research, known by its French acronym, cern, is an almost unimaginably long-term project. It was conceived a quarter-century ago, was given the green light in 1994, and has been under construction for the last 13 years, the product of tens of millions of man-hours. It’s also gargantuan: a circular tunnel 17 miles around, punctuated by shopping-mall-size subterranean caverns and fitted out with more than $9 billion worth of steel and pipe and cable more reminiscent of Jules Verne than Steve Jobs.

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The Circular Logic of the Universe

From Natalie Angier, New York Times.

Circling my way not long ago through the Vasily Kandinsky show now on display in the suitably spiral setting of the Guggenheim Museum, I came to one of the Russian master’s most illustrious, if misleadingly named, paintings: “Several Circles.” blog1

Those “several” circles, I saw, were more like three dozen, and every one of them seemed to be rising from the canvas, buoyed by the shrewdly exuberant juxtapositioning of their different colors, sizes and apparent translucencies. I learned that, at around the time Kandinsky painted the work, in 1926, he had begun collecting scientific encyclopedias and journals; and as I stared at the canvas, a big, stupid smile plastered on my face, I thought of yeast cells budding, or a haloed blue sun and its candied satellite crew, or life itself escaping the careless primordial stew.

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Scientists Grow Pork Meat in a Laboratory

pig1

From The Sunday Times

Scientists have grown meat in the laboratory for the first time. Experts in Holland used cells from a live pig to replicate growth in a petri dish.

The advent of so-called “in-vitro” or cultured meat could reduce the billions of tons of greenhouse gases emitted each year by farm animals — if people are willing to eat it.

So far the scientists have not tasted it, but they believe the breakthrough could lead to sausages and other processed products being made from laboratory meat in as little as five years’ time.

They initially extracted cells from the muscle of a live pig. Called myoblasts, these cells are programmed to grow into muscle and repair damage in animals.

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