Monthly Archive for July, 2010

The Human Genome at Ten

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From Nature

Nearly a decade on from the completion of the draft sequence of the human genome, researchers should work with the same intensity and focus to apply the results to health.

The race to complete the first human genome sequence had everything a story needs to keep its audience enthralled — right down to a neck-and-neck sprint for the finish by two fierce rivals. In the end, the result was basically a tie. The rivals — the international, publicly funded Human Genome Project and the private, for-profit company Celera Genomics then based in Rockville, Maryland — jointly announced the completion of their draft sequences in June 2000 at a gala televised press conference attended by US President Bill Clinton and UK Prime Minister Tony Blair.

The White House press statement articulated the hope, felt by many, that this landmark achievement would “lead to a new era of molecular medicine, an era that will bring new ways to prevent, diagnose, treat and cure disease”.

This issue of Nature takes a look at the next chapter in the story — the first post-genome decade — then asks how the tale might unfold in the years to come.

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Collaborating with Citizen Scientists

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From Lucas Laursen, Science

Climbing one of the world’s biggest granite walls is different from climbing trees, as National Park Service botanist Martin Hutten discovered while dangling from a cliff in the spray of Vernal Falls high above the Yosemite Valley. Hutten apprenticed in the logging industry before he started graduate school, so he new how to climb trees. “I could trust myself to a rope,” he recalls, “but I’d definitely never hung off a cliff or collected [samples] from a cliff.”

So when Hutten — who is seeking a Ph.D. in forest ecology at Oregon State University, Corvallis — and his fellow park rangers needed help surveying the park’s lichen, they enlisted experienced rock climbers. Over 2 weeks in 2007 and 2008, those volunteer climbers helped collect 394 lichen specimens. This year, the researchers are asking volunteers to help with other parts of their biodiversity survey, such as counting birds from the valley floor.

Hutten’s project is one of many worldwide in which volunteers help scientists collect data in ways that range from mundane to vital. Such help, although voluntary, is not free. Recruiting volunteers, finding appropriate ways for them to contribute, training them, keeping them motivated, and ensuring the quality of the data they collect requires time, money, and management expertise.

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